Event Date
Titia de Lange, Leon Hess Professor; Director of the Anderson Center for Cancer Research, The Rockefeller University
An internationally recognized leader in chromosome biology, de Lange's research focuses on telomeres—the protective DNA-protein structures at the ends of chromosomes that preserve genome integrity and shorten with cell division. De Lange discovered and characterized shelterin, a six-protein complex that safeguards telomeres from being mistaken for damaged DNA, and helped reveal the t-loop structure that hides chromosome ends from DNA damage responses. Her work has defined how telomere dysfunction contributes to genome instability and cancer, including the mechanisms underlying telomere crisis and chromosomal rearrangements. By combining molecular, structural, and cellular approaches, her lab investigates how telomeres are replicated and maintained and how telomere shortening acts as a powerful tumor-suppressive mechanism. De Lange is the recipient of numerous honors, including the Breakthrough Prize in Life Sciences for her transformative contributions to telomere biology.
***Zoom Information will be provided to registrants. Registration link is forthcoming.***
Agenda:
- 4:00pm - doors open
- 4:10pm - introductory remarks
About the Series:
The Tracy and Ruth Storer Lectureship in the Life Sciences is the most prestigious of the endowed seminars at UC Davis. Established in 1960, the Storer Endowment makes it is possible to invite distinguished biological scientists to campus to present two lectures and meet with faculty members and graduate students in their field of interest. The series is presented by the UC Davis College of Biological Sciences.