Research Stories

Can Diet Help Prevent or Postpone Cognitive Decline?

In a review article published in Nature: Science of Food, Professor Raymond Rodriguez and his colleagues explore the relationship between diet and brain health, proposing a framework to understand the body’s “food-brain axis,” the intersection of diet and the formation of new brain cells. Rodriguez’s aim is to provide researchers with a dietary roadmap to help prevent cognitive decline.

Photosynthesis Requires the Blue-Greens

How did plants develop photosynthesis? The story is really nothing more than a tale of biological thievery. Publishing in The Plant Cell, Lagarias and his colleagues found that a pigment called biliverdin is essential to light-induced chlorophyll production in the alga. This discovery is helping scientists understand why diverse algae retain these pigments, although many lack phytochromes.

Connecting the Molecular Dots of Heart Disease

Associate Professor Aldrin Gomes, Department of Neurobiology, Physiology and Behavior in the College of Biological Sciences at UC Davis, studies the underpinnings of heart disease, focusing on the machinery within heart cells responsible for producing the heartbeat. Along with colleagues in the Gomes Lab, he’s searching for molecular clues that will help medical professionals better manage heart disease.

Zebrafish Reproductive Development May Hold Insights into Ovarian Cancer

With funding from the National Institutes of Health and the National Science Foundation, Associate Professor Bruce Draper, Department of Molecular and Cellular Biology, is studying zebrafish (Danio rerio) to learn about the genetics of sexual reproduction in vertebrates. Draper’s research, published in PLOS Genetics with postdoc and Dena Leerberg, ’17 Ph.D., may advance discoveries into the origins of ovarian cancer.

Knotty Problems: Mariel Vazquez Shares How E. Coli Reconnects Tangled DNA 

If you’ve ever tried to untangle a pair of earbuds, you’ll understand how loops and cords can get twisted up. DNA can get tangled in the same way, and in some cases, has to be cut and reconnected to resolve the knots. Now a team of mathematicians, biologists and computer scientists has unraveled how E. coli bacteria can unlink tangled DNA by a local reconnection process. The math behind the research, recently published in Scientific Reports, could have implications far beyond biology.

“Smart” Immune Cells: Emerging Cancer Therapy Research at UC Davis Receives a Boost with NIH Award

Assistant Professor Sean Collins, Department of Microbiology and Molecular Genetics, has received a $1.5 million award from the National Institutes of Health to advance the development of “smart” immune cells for therapies to treat cancer and other diseases. The five-year NIH Director’s New Innovator Award aims to provide new insight into how to engineer immune cells to control their recruitment and response to tumors.