Extramurally Funded Research

A Mixed Origin Made Maize Successful

Maize is one of the world’s most widely grown crops. It is used for both human and animal foods and holds great cultural significance, especially for indigenous peoples in the Americas. Yet despite its importance, the origins of the grain have been hotly debated for more than a century. Now new research, published Dec. 1 in Science, shows that all modern maize descends from a hybrid created just over 5000 years ago in central Mexico, thousands of years after the plant was first domesticated.

Understanding Neutrophil Decision-Making: How Immune Cells Prioritize Competing Signals

Neutrophils, the primary foot soldiers of the immune system, swarm to sites of infection and inflammation by following breadcrumb pathways made up of signaling molecules. But the human body is a complex place, and neutrophils are often simultaneously bombarded with multiple signals, some of which are more important than others. For example, signals of infection or tissue damage require more urgent attention than signals produced by other immune cells.

How Sunflowers See the Sun

Sunflowers famously turn their faces to follow the sun as it crosses the sky. But how do sunflowers “see” the sun to follow it? New work from plant biologists at the University of California, Davis, published Oct. 31 in PLOS Biology, shows that they use a different, novel mechanism from that previously thought.

“This was a total surprise for us,” said Stacey Harmer, professor of plant biology at UC Davis and senior author on the paper.

Chloroplasts Do More Than Photosynthesis; They’re Also a Key Player In Plant Immunity

Scientists have long known that chloroplasts help plants turn the sun’s energy into food, but a new study, led by researchers in the Department of Plant Biology, shows that they’re also essential for plant immunity to viral and bacterial pathogens.

Chloroplasts are generally spherical, but a small percentage of them change their shape and send out tube-like projections called “stromules.” First observed over a century ago, the biological function of stromules has remained enigmatic.

Experiments in Yeast Hint at Possible Origins of Cancer and Autism

Cancer often starts with the reshuffling of DNA—akin to scrambling the pages of a dictionary. Exactly how this happens has long been a mystery. But researchers in the UC Davis College of Biological Sciences have now arrived at one promising explanation.

The problem seems to happen at a critical moment: when the cell is fixing a broken string of DNA. This repair process, called homologous recombination, can go awry, says Wolf-Dietrich Heyer, a Distinguished Professor and chair in the Department of Microbiology and Molecular Genetics.

NIH Awards Priya Shah $2.8 Million to Research How Zika Virus Causes Brain-Related Birth Defects

For most people, contracting Zika virus, a flavivirus carried by mosquitos, is akin to getting any mildly inconvenient virus. 

You might get a fever and a rash, and it's gone in a few days. But for pregnant people, there is a roughly 4% chance that a bite from a mosquito with Zika virus could have life-altering effects on developing fetuses in the form of microcephaly, a neurological condition that indicates an under-developed brain.  

Genome Study Shows Recent Spread of Eelgrass

Beds of eelgrass (Zostera marina) form an important habitat in coastal regions throughout the northern hemisphere, crucial to many fish and other species and storing vast amounts of carbon. A new study published July 20 in Nature Plants shows that eelgrass spread around the world much more recently than previously thought, just under a quarter-million years ago. The results have implications for how eelgrass could be affected by a changing climate.

Using Machine Learning to Detect Coronavirus Threats

An artificial intelligence model has successfully identified coronaviruses capable of infecting humans, out of the thousands of viruses that circulate in wild animals. The model, developed by a team of biologists, mathematicians and physicists at the University of California, Davis, could be used in surveillance for new pandemic threats. The work was published June 8 in Scientific Reports.